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Additionally, the positive outcomes of ongoing trials SURPASS-CVOT and SURMOUNT-MMO will provide definitive evidence regarding the cardiovascular safety and efficacy of tirzepatide compared to dulaglutide and reduction in morbiditiy and mortality in adults with obesity respectively

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Massey, Lerner Research Institute, Cleveland Clinic, United States Updates Copyright 2025 Karimi, Gholami Chahkand, Dadkhah, Sheikhzadeh, Yaghoubi, Esmaeilpour Moallem, Deyhimi, Arab Bafrani, Shahrokhi and Nasrollahizadeh

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Metabolic Boost: By activating the glucagon receptor, it increases resting energy expenditure, helping you burn more fat even while at rest

The reason is that intravenous administration carries a risk of immunogenicity the immune system recognizes Serratiaderived molecular signatures on the enzyme as foreign, which can trigger immune reactions